Search results for "Takemoto’s catalyst"

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Thiourea Organocatalysts as Emerging Chiral Pollutants: En Route to Porphyrin-Based (Chir)Optical Sensing

2021

Environmental pollution with chiral organic compounds is an emerging problem requiring innovative sensing methods. Amino-functionalized thioureas, such as 2-(dimethylamino)cyclohexyl-(3,5-bis(trifluoromethyl)phenyl)thiourea (Takemoto’s catalyst), are widely used organocatalysts with virtually unknown environmental safety data. Ecotoxicity studies based on the Vibrio fischeri luminescence inhibition test reveal significant toxicity of Takemoto’s catalyst (EC50 = 7.9 mg/L) and its NH2-substituted analog (EC50 = 7.2–7.4 mg/L). The observed toxic effect was pronounced by the influence of the trifluoromethyl moiety. En route to the porphyrin-based chemosensing of Takemoto-type thioureas, their s…

Circular dichroismSupramolecular chemistrychiralitymonitorointiEnvironmental pollutionchiral amineVibrio fischeriQD415-436010402 general chemistryBiochemistry01 natural sciencesMedicinal chemistrysupramolecular chemistrybakteeritAnalytical Chemistry<i>Vibrio</i> <i>fischeri</i>chemistry.chemical_compoundkatalyytitrikkiyhdisteetsupramolekulaarinen kemiaMoiety[CHIM]Chemical Sciences[CHIM.COOR]Chemical Sciences/Coordination chemistryPhysical and Theoretical Chemistrythioureaorgaaniset yhdisteetchiral pollutantsTrifluoromethyl010405 organic chemistrytoxicityhost–guest bindingPorphyrin0104 chemical sciencesTakemoto’s catalystcircular dichroismekotoksikologiachemistryThiourea13. Climate action[SDV.TOX.ECO]Life Sciences [q-bio]/Toxicology/Ecotoxicology[SDE.BE]Environmental Sciences/Biodiversity and EcologyChirality (chemistry)porphyrinorganocatalyst
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